Smoking and oropharyngeal cancer

Please write a 500 word paper which summarizes the epidemiological association between smoking and oropharyngeal cancer. Please include at least one paragraph which specifically mentions HPV-positivity. Please see the 2008 publication “Distinct Risk Factor Profiles for Human Papillomavirus Type 16 – Positive and Human Papillomavirus Type 16 – Negative Head andNeck Cancers” by
Maura L. Gillison et al. My paper is essentially an updated literature review that will be very similar to the introduction to this paper.